What is the Cholesterol?

Cholesterol is White to faintly yellow cryst. powder, while it's Molecular Formula is C27H46O. White to faintly yellow cryst. powder Cholesterol be used as pharmaceutical intermediates and be used as synthetic materials of liquid crystal polymers.

What is the CAS number for Cholesterol?

The CAS number of Cholesterol is 57-88-5.

What is Cholesterol (57-88-5) used for?

Cholesterol is a soft waxy substance that is a steroidal alcohol or sterol. It is the most abundantsteroid in the human body and is a component of every cell. Cholesterol is essential to lifeand most animals and many plants contain this compound. Cholesterol biosynthesis occursprimarily in the liver, but it may be produced in other organs. A number of other substancesare synthesized from cholesterol including vitamin D, steroid hormones (including the sexhormones), and bile salts. Cholesterol resides mainly in cell membranes.Humans produce about 1 gram of cholesterol daily in the liver. Dietary cholesterol is consumedthrough food. High cholesterol foods are associated with saturated fats and trans-fattyacids (commonly called trans fats). Dietary cholesterol comes from animal products (plantscontain minute amounts of cholesterol) such as meats and dairy products.InChI:InChI=1/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

Chinese Factory Supply High Purity 99% 57-88-5 Efficient Shipping

Product Details;

CasNo： 57-88-5

Molecular Formula： C₂₇H₄₆O

Appearance： White to faintly yellow cryst. powder

Chinese Factory Supply High Purity 99% Cholesterol 57-88-5 Efficient Shipping

Molecular Formula:C27H46O
Molecular Weight:386.662
Appearance/Colour:White to faintly yellow cryst. powder
Vapor Pressure:2.95E-11mmHg at 25°C
Melting Point:148-150 °C
Refractive Index:1.525
Boiling Point:480.648 °C at 760 mmHg
PKA:15.03±0.70(Predicted)
Flash Point:209.291 °C
PSA：20.23000
Density:0.988 g/cm³
LogP:7.38870

Cholesterol(Cas 57-88-5) Usage

Description	Cholesterol is a lipid that plays a crucial role in various physiological functions, including cell membrane structure, hormone synthesis, and overall metabolic balance.
Physical Characteristics	Appearance: White to faintly yellow crystalline powder. First discovered in 1769 by Poulletier dela Salle, isolated from bile and gallstones.
Physiological Importance	Vital for physiological functions but emphasizes the importance of maintaining healthy levels to prevent atherosclerosis and associated cardiovascular risks. Occurs in the intestines, and dietary cholesterol is absorbed in the form of chylomicrons into the bloodstream.
Distribution in the Body	A normal person weighing 70 kg contains about 140 grams of cholesterol in the body. Rough distribution in various tissues is relatively stable.
Roles in the Body	Formation of cell membranes. Raw material for the synthesis of bile acids, vitamin D, and steroid hormones. Stable total serum cholesterol levels are crucial for overall health.
Cholesterol Transport	Two major lipoproteins involved in cholesterol transport: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL transports cholesterol from the liver to body tissue cells, while HDL transports cholesterol from tissue cells back into the liver.
Industrial Uses	Employed in the production of artificial bezoar and the preparation of hormone drugs. Used in the pharmaceutical and cosmetic industries for its emulsifying and emollient properties.
Synthesis and Purification	Commercially obtained from the spinal cord of cattle by extraction with petroleum ethers. Purification is achieved by repeated bromination, and cholesterol may also be produced synthetically.
Definition	ChEBI: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Hazard	Questionable carcinogen.
Safety Profile	Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. Used in pharmaceutical and dermal preparations as an emulsifying agent. When heated to decomposition it emits acrid smoke and irritating fumes.
storage	Cholesterol is stable and should be stored in a well-closed container, protected from light.

InChI:InChI=1/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

57-88-5 Relevant articles

Stereochemical Fate of the Isopropylidene Methyl Groups of Lanosterol during the Biosynthesis of Isofucosterol in Pinus Pinea

Nicotra, Francesco,Ronchetti, Fiamma,Russo, Giovanni,Lugaro, Giuseppe,Casellato, Marilena

, p. 498 - 502 (1981)

Lanosterol (16) was administered to Pinu...

Highlights of the report of the expert panel on blood cholesterol levels in children and adolescents

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, By National Cholesterol Education Program (U.S.). Expert Panel on Blood Cholesterol Levels in Children and Adolescents

… blood cholesterol levels and higher intakes of saturated fatty acids and cholesterol, and US adults have higher blood cholesterol levels and higher rates of CHD morbidity and mortality. …

Reduction of Blood Cholesterol in Man

O. J. POLLAK

， Circulation. 1953;7:702–706

Excess supply of plant sterol was required in clinical experiments because the material used contained but 75 to 80 per cent of sitosterol and because of the large amount of endogenous cholesterol which has to be inactivated by the sitosterol, besides exogenous cholesterol.

Method for preparing cholesterol and derivatives thereof by taking phytosterol as raw material

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Paragraph 0065, (2021/02/20)

The invention discloses a method for pre...

57-88-5 Process route

: 80239-44-7
1α-Hydroxy-5-cholesten-3-on

: 57-88-5
cholesterol

: 50392-20-6
5-Cholesten-1α,3α-diol

: 26358-75-8
1α,3β-dihydroxycholest-5-ene

Conditions

Conditions	Yield
With lithium; ammonium chloride; In diethyl ether; ammonia; at -33 ℃; for 0.5h; Yield given. Yields of byproduct given;

: 79824-96-7
(4-nitro-phenyl)-cholesteryl carbonate

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 124-38-9,18923-20-1
carbon dioxide

: 57-88-5
cholesterol