CasNo: 129954-34-3
Molecular Formula: C33H57N11O9
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Selank peptide is , while it's Molecular Formula is C33H57N11O9.
The CAS number of Selank peptide is 129954-34-3.
More information of Selank peptide 129954-34-3 are:
|
CAS Number |
129954-34-3 |
|
Molecular Formula |
C33H57N11O9 |
|
Molecular Weight |
0.00000 |
|
Density |
1.53±0.1 g/cm3(Predicted) |
|
Melting Point |
134-136 °C |
|
PSA |
0.00000 |
|
LogP |
0.00000 |
|
Pka |
3.43±0.20(Predicted) |
Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg.
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