CasNo： 149-44-0
Molecular Formula： CH3NaO3S
Appearance： solid
Rongalite, also known as sodium bisulfite formaldehyde, is a versatile compound with various applications in industries such as textiles, dyes, and organic synthesis. Here is detailed information about Rongalite:
Industrial Applications:
Widely used in the textile and dye industry as a bleaching agent and reducing agent in redox reactions.
Employed in the printing and dyeing industry to produce discharging agents.
Acts as an activator in styrene-butadiene rubber (SBR) polymerization.
Organic Synthesis:
Functions as a powerful reagent in organic synthesis.
Particularly useful for the preparation of sultines and sulfones due to its capability to deliver SO2 dianion.
Promotes a smooth, one-pot synthesis of aryl alkyl sulfides from disulfides and alkyl halides at room temperature.
Chemical Composition:
Chemical name: Sodium bisulfite formaldehyde.
Molecular formula: Not explicitly mentioned, but it is a white solid compound.
Textile Industry:
Used as a stripping and discharge agent in textiles.
Plays a crucial role in the bleaching and coloration processes in the textile industry.
Pharmaceutical Applications:
Applied in pharmaceuticals as a preservative and pharmaceutical aid.
Its use in the pharmaceutical industry indicates its role in certain formulations and processes.
InChI:InChI=1/CH3O3S.Na/c2-1-4-5-3;/h2H,1H2;/q+1;-1/rCH3NaO3S/c2-6(4)5-1-3/h3H,1H2
A concise and efficient hydrodefluorination process was developed for the synthesis of gem-difluoroalkenes. This reaction employs rongalite as a masked proton source and does not require any additional catalysts or reductants. Notably, trifluoromethyl alkenes having both terminal and internal double bonds are compatible with this process, allowing for a wider range of substrates. The successful late-stage functionalizations of pharmaceuticals and gram-scale syntheses were used to demonstrate the viability of this method.
A crystal-structure determination has shown that the compound of empirical formula NaHS0,. H. CH0, 2H20 is sodium hydroxymethanesulphinate dihydrate.
formaldehyd
Sodium; 2,2,2-trifluoro-1-hydroxy-ethanesulfinate
2,2,2-trifluoro-1,1-ethanediol
rongalite
| Conditions | Yield |
|---|---|
|
In water-d2; Yields of byproduct given. Title compound not separated from byproducts;
|
|
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In water-d2; Yield given. Title compound not separated from byproducts;
|
formaldehyd
rongalite
| Conditions | Yield |
|---|---|
|
With sodium Oleate; sodium hydrogensulfite; zinc; In water; at 94 ℃; for 4h; further added surfactants; influence od electrodeposited zinc on synthesis;
|
86% |
|
With sodium hydrogensulfite; zinc;
|