CasNo: 50-28-2
Molecular Formula: C18H24O2
Appearance: white crystalline powder
Description |
β-Estradiol, also known as 17β-estradiol, E2, or 17β-Oestradiol, is a critical human sex hormone and steroid that serves as the primary female sex hormone. β-Estradiol is a fundamental hormone with diverse functions in the female reproductive system. Its role extends beyond reproductive health, influencing bone health and other physiological processes. |
Contradictions |
Do not use on breasts, vaginal area and vaginal mucosa. |
Uses |
Functions as an endogenous estrogenic hormone receptor (ER) agonist. |
Medical Applications | Used for in vitro maturation of bovine cumulus-oocyte complexes (COCs). Implicated in hormone replacement therapy (HRT) for postmenopausal women. |
Definition |
ChEBI: The 17beta-isomer of estradiol. |
Hazard |
A carcinogen (OSHA). |
Shipping |
UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials |
Who Evaluation |
Evaluation year: 2000 |
InChI:InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m0/s1
Androgen (5α-dihydrotestosterone) did not. Castration of male or female mice did not affect natural killing and did not alter the effect of β-estradiol. Estradiol did not affect natural killing in vitro and the loss of natural killing was not due to a soluble or a cellular suppressor of natural killing.
At 10−8 M, congener 114, a weak EROD inducer, potentiated Vg synthesis relative to cells treated with β-estradiol alone.
Bolandiol is a synthetic anabolic steroi...
Androstenedione
estradiol
Estrone
testosterone
Stanolone
Etiocholanolone
cis-androsterone
Conditions | Yield |
---|---|
With carcinoma; gynecomastia; mammary dysplasia; at 37 ℃; for 1.5h; Product distribution; cofactors under 95percent O2: 5percent CO2, <3H>labeled study;
|
17β-estradiol 3'-(saccharinylmethyl) ether
formaldehyd
estradiol
saccharin
Conditions | Yield |
---|---|
With phosphate buffer; water; In methanol; at 37 ℃; Rate constant; various pH-values (4.98-7.98); half-life; other media, other temperature;
|
quinoline
1-dehydrotestosterone
1,3,5-trinitrobenzene
Estrone
17β-oestradiol diacetate
17-β-estradiol 17-acetate
2-iodo-17β-oestradiol
2-bromo-17β-oestradiol