CasNo： 22801-44-1
Molecular Formula： C15H22N2O
Mepivacaine acts as a local anesthetic by blocking nerve impulses. It works by inhibiting sodium ion influx through sodium-specific ion channels in the neuronal cell membrane. This action prevents the generation and conduction of nerve impulses, leading to temporary numbing of the targeted area. We supply high quality Mepivacaine (CAS 22801-44-1), in stock, factory directly supply to clients, lower prices, more competitiveness.
Mepivacaine is a piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond., while it's Molecular Formula is C15H22N2O. Local anesthetic.
The CAS number of Mepivacaine is 22801-44-1.
More information of Mepivacaine 22801-44-1 are:
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Synonyms |
2-piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-;N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide;DL-Mepivacaine; |
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CAS Number |
22801-44-1 |
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Molecular Formula |
C15H22N2O |
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Molecular Weight |
246.35 |
|
Density |
1.077 g/cm3 |
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Boiling Point |
383.1 °C at 760 mmHg |
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Flash Point |
185.5 °C |
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PSA |
32.34000 |
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LogP |
2.73710 |
|
Pka |
pKa 7.73(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain) |
Mepivacaine is a local anesthetic used for local or regional analgesia or anesthesia. It belongs to the class of amide-type local anesthetics. Mepivacaine solutions may include a vasoconstrictor, such as epinephrine. The addition of epinephrine can help to prolong the duration of the anesthetic effect by reducing local blood flow and increasing the concentration of the drug at the site of action. However, the use of mepivacaine with epinephrine should be approached with caution in certain patient populations, particularly those receiving monoamine oxidase inhibitors (MAOIs) or certain types of antidepressants.
InChI:InChI=1/C15H22N2O/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18)
Articles related to Mepivacaine:
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Article |
Source |
| Efficacy and safety of mepivacaine compared with lidocaine in local anaesthesia in dentistry: a meta-analysis of randomised controlled trials |
Naichuan Su 1 2, Yan Liu 1 3, Xianrui Yang 1 4, Zongdao Shi 1 5, Yi Huang 1 4 , International Dental Journal Volume 64, Issue 2, April 2014, Pages 96-107 The objective of the study was to assess the efficacy and safety of mepivacaine compared with lidocaine used in local anaesthesia in dentistry. Medline, Cochrane Central Register of Controlled Trials, EMBASE, Chinese BioMedical Literature Database, China National Knowledge Infrastructure and WHO International Clinical Trials Registry Platform were searched electronically. |
| Epidural block with mepivacaine before surgery reduces long-term post-thoracotomy pain |
Hideaki Obata, Shigeru Saito, Nao Fujita, Yoshiaki Fuse, Keiji Ishizaki & Fumio Goto Canadian Journal of Anesthesia, Volume 46, pages 1127–1132, (1999) In a double-blind study, 70 patients scheduled for thoracic surgery under general anesthesia were assigned randomly to receive continuous epidural block with mepivacaine 1.5% initiated either 20 min before surgical incision (Pre group) or at completion of surgery (Post group). |
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